Travel Interstate 40 West. After Winston-Salem, take exit 188 for Hwy 421 North, toward Yadkinville and Wilkesboro; merge onto Hwy 421.  Follow Option 2.

*The Blue Ridge Parkway is closed in the Boone and Blowing Rock area (Milepost 285.5 - 291.8) due to repairs on Goshen Creek Bridge.  The repair is anticipated to be finished in late December 2008.*

Option 1 (Good Weather):Exit Hwy 421 North to the Blue Ridge Parkway, Southbound. Continue South on the Parkway until just past the Moses Cone Manor House. Exit the Parkway between mile marker 294 and 295 toward Blowing Rock and Hwy 221. Drive 50 feet into the exit, then turn right onto Shulls Mill Road. Follow Shulls Mill Road for 2.6 miles. Entrance to the Inn at Yonahlossee is on the left across from the main entrance to the Resort.

Option 2 (Fog or Snowy):Continue on Hwy 421 North into Boone. After New Market Center (Lowes Foods, Hardees, Regal Cinemas) on the right, turn left at the stoplight onto Hwy 105 South. There is a service station on the left and Blue Ridge Bedrooms is on the opposite corner. Follow Hwy 105 South for 2.8 miles. Just after the Highland Commons Shopping Center (Ingle's and CVS)on your left and just before the "Tomato Shack," turn left onto Poplar Grove Road. Follow Poplar Grove Road for 3.8 miles until it ends at Shulls Mill Road. Turn left onto Shulls Mill Road. The entrance to the Inn at Yonahlossee is 300 yards ahead on the right.